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3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
| Product Name | 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Product Code | A00007015 |
| Chemical name | 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Synonyms | INK 128; MLN 0128; Sapanisertib |
| Impurity | |
| CAS Number | 1224844-38-5 |
| Alternate CAS # | |
| Molecular form | C₁₅H₁₅N₇O |
| Appearance | White to Off-White Solid |
| Melting Point | 270-272ºC (dec.) |
| Mol. Weight | 309.33 |
| Storage | Hygroscopic, Refrigerator, under inert atmosphere |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Stability | Hygroscopic |
| Category | Amines, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals |
| Boiling Point | |
| Applications | 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a potent and selective TORC1/2 inhibitor with broad oral antitumor activity. TORC1/2 inhibitors are mechanistically distinct from rapamycinand offer a compelling approach to the treatment of cancer by targeting translational control, cell metabolism, growth andangiogenesis. |
| Dangerous Goods Info | |
| References | Katayoun, J., et al.: Molec. Cancer. Therap., 8, 1158 (2009); |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
| Keywords | Buy 1224844-38-5 | Purchase 1224844-38-5 | Order 1224844-38-5 | 1224844-38-5 supplier | 1224844-38-5 manufacturer | 1224844-38-5 distributor | 1224844-38-5 cost |
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